RBV + Denarii Labs Weekly Newsletter 🧔📖 Week of 3/05/26

Welcome to the latest edition of the Red Beard Ventures newsletter, where we dive into exciting updates and insights from all over our portfolio and network!

📣 As a reminder, Red Beard Ventures has a syndicate, fund, tokenomics accelerator, and Web3 consultancy:

• The Red Beard Ventures Syndicate is stage agnostic and invests in Frontier Technology with a focus on Web3, Space, FinTech, Sports, Robotics, Biotech, and Climate. We invest anywhere between $100k - $1.5M. 

• Red Beard Ventures Fund I invests $100k - $1M in Pre-seed and Seed blockchain based companies.

• Denarii Labs is a tokenomics accelerator which invests $100k into companies interested in designing and launching a token over a twelve week hands-on program. Denarii also features a consulting business for later stage clients with higher touchpoint needs in tokenomics, communications, growth, and marketing.

🎤 RBV / Denarii Labs Announcements:

Denarii Labs Cohort 4 - Applications Now Open for Cohort 4

Denarii Labs is now accepting applications for Cohort 4. We are actively reviewing applications and investing $100K into projects looking to design, launch, and scale their token ecosystems over a 12 week program. Apply now to join a network of high-conviction builders shaping the next generation of on-chain economies.

One Spot Left!

Join our current accelerator alongside Canton and Starknet. We've previously run accelerator programs for Avalanche, Hedera, Flow, Xion & more.

If you'd like to partner with RBV/Denarii for an accelerator, DM Sean Melcher 

Looking for funding? Link to apply

🚀 RBV Spotlight:

Coinrule Expands AI Trading Platform Beyond Crypto

Coinrule continues to expand its AI-driven trading automation platform, with models now trained on more than 1.7 million real trading strategies executed across multiple market cycles. This large dataset allows the platform to continuously refine strategies and help users automate sophisticated trading decisions without requiring deep quantitative expertise.

The company also announced a major product expansion beyond crypto, integrating seven new broker partners to support equities and ETFs. This unlocks access to a significantly larger global trading market while allowing users to deploy automated strategies across both digital assets and traditional financial instruments.

By combining AI-powered strategy generation with cross-asset trading infrastructure, Coinrule is positioning itself as an automation layer for modern financial markets, enabling both retail and professional traders to execute systematic strategies across crypto and traditional assets.

Congratulations to the Coinrule team! 🚀

💼 Portfolio News:

Colossal Biosciences advances de-extinction pipeline across multiple species

• Advancing multiple de-extinction programs including the dire wolf, moa, dodo, thylacine, and woolly mammoth.
• Shared a real-time Q&A thread with videos and GIFs highlighting technical progress and team engagement.
• Combines genomics and AI-driven biotech with massive long-term IP and storytelling potential.

QuickNode releases Polygon builder resource hub for developers

• Released a one-stop toolkit for Polygon developers including RPC docs, guides, and a testnet faucet.
• Supports JSON-RPC, REST, gRPC, and WebSocket for seamless developer onboarding.
• Strengthens ecosystem infrastructure and accelerates L2 developer adoption.

HYTOPIA open-sources its game engine to accelerate builder ecosystem

• Released its game engine under an MIT license, enabling anyone to use, fork, or contribute on GitHub.
• Unlocks faster experimentation and local development for creators building block-style games.
• Expands the builder ecosystem and strengthens the metaverse gaming flywheel.

KNOX introduces structured tranche products for institutional DeFi yield

• Introduced structured DeFi yield products offering fixed-rate, uncapped, or risk-defined tranches.
• Allows institutions to match exact risk appetite while using the same underlying yield strategies.
• Brings TradFi-style structured products to DeFi capital markets.

DFNS integrates Global Ledger compliance data into wallet policy services

• Integrated Global Ledger’s compliance data directly into DFNS wallet policy services.
• Moves compliance checks before transaction execution, improving institutional security workflows.
• Strengthens DFNS as programmable wallet infrastructure for regulated crypto applications.

Fhenix advances encrypted blockchain infrastructure using FHE

• Emphasizes a future where all blockchain transactions are encrypted by default.
• Developing FHE-powered infrastructure to enable private computation directly onchain.
• Signals growing momentum around privacy-preserving smart contracts and confidential DeFi.

Saga pushes AI agents toward production across gaming and entertainment

• Announced plans to bring AI agents into production with gaming studios, sports organizations, and entertainment IP.
• Saga’s Becca Liao will speak at EthCC on turning autonomous systems into onchain economic actors.
• Highlights Saga’s role in powering the emerging agentic economy.

Truflation publishes real-time inflation index amid geopolitical shifts

• Inflation index currently at 0.96% while tracking geopolitical developments in real time.
• Uses 35M+ daily data points to deliver faster macro insights than traditional statistics.
• Provides valuable signals for DeFi markets, trading strategies, and macro portfolio analysis.

bitsCrunch builds MCP integration for AI-accessible onchain data

• Building MCP support so AI systems can directly access NFT, wallet, and market intelligence.
• Enables structured blockchain data feeds for autonomous agents and analytics tools.
• Positions bitsCrunch as a core data layer for AI-native crypto applications.

Paradromics CEO discusses BCI race toward FDA approval

• CEO Matt Angle discussed the state of the brain–computer interface industry in a STAT article.
• Highlights accelerating regulatory progress toward FDA approval for neural implants.
• Reinforces Paradromics’ leadership in next-generation neural interface technology.

🚀 Onwards!

Drew, Elana, Joshua, Lauren, and Jeff